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I think the rust issue is a good point. However, if you are tying to something that does not rust or accumulate salt and you are using a highly rated knot (google fishing knot ratings), you should not run into problems for at least weeks if not months. A good knot tends to be one that does not excessively bind on itself or the part being tied to so there should be little degradation of the line from staying tied. However, as mentioned, the knots should have been lubed up before tightening in the first place. Also, once you have put the stress of a large fish on the knot, it may be binding on itself making it weaker. So, if you tie a bad knot type or don't moisten the line before tightening or fish the knot after working in a big fish, you are pushing your luck. That is my take, but I am definitely no mono/fluro expert.
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